A Randomised Controlled Trial of Efficacy of Cognitive Rehabilitation in Multiple Sclerosis: A Cognitive, Behavioural, and MRI Study

A Randomised Controlled Trial of Efficacy of Cognitive Rehabilitation in Multiple Sclerosis: A Cognitive, Behavioural, and MRI Study

The Effectiveness of Cognitive-Behavioral Therapy in Pain Self-Efficacy, Fatigue, Life Expectancy and Depression in Patients with Multiple Sclerosis (MS): A Randomized Controlled Clinical Trial

Objective: The present study was conducted to investigate the effectiveness of cognitive-behavioral therapy in pain self-efficacy, fatigue, life expectancy and depression in patients with multiple sclerosis (MS). Methods: In a semi-experimental research with a control group pretest-posttest design, 68 patients with multiple sclerosis (MS) were selected through convenience sampling from neurolo...

Cognitive Rehabilitation for Attention and Memory in people with Multiple Sclerosis: study protocol for a randomised controlled trial (CRAMMS)

BACKGROUND People with multiple sclerosis have problems with memory and attention. Cognitive rehabilitation is a structured set of therapeutic activities designed to retrain an individual's memory and other cognitive functions. Cognitive rehabilitation may be provided to teach people strategies to cope with these problems, in order to reduce the impact on everyday life. The effectiveness of cog...

The Effectiveness of Cognitive Rehabilitation on Cognitive Flexibility, Response Inhibition, and Selective Attention in Patients with Multiple Sclerosis: A Quasi-Experimental Study

Background & Aims: Multiple sclerosis (MS) is the most common cause of disability with cognitive impairments. The current study aimed to investigate the effect of cognitive rehabilitation (CR) on cognitive flexibility, response inhibition, and selective attention in patients with MS. Materials and Methods: The current quasi-experimental study with a pretest-posttest plot and a control group wa...

A Comparison Study of Efficacy and Safety of a Biosimilar Form of Intramuscular Βeta-interferon I-a Versus the Reference Product: A Randomized Controlled Clinical Trial in Iran

We compared the efficacy and safety of a biosimilar form of beta-interferon-1a (Actovex) versus the reference product in the treatment of relapsing remitting multiple sclerosis (RRMS). In a double blind, randomized phase 3 clinical trial, we evaluated 138 patients with RRMS that were allocated to receive the biosimilar medication and the reference treatment (30 μg intramuscular, weekly for one ...